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Ultima Pharmaceuticals is a prominent pharmaceutical company that specializes in the production and distribution of high-quality medical products. With a strong commitment to innovation, research, and development, Ultima Pharmaceuticals aims to improve the quality of life for individuals worldwide.
The company prides itself on adhering to stringent standards of quality control and compliance, ensuring that all its products meet the highest levels of safety and efficacy. Ultima Pharmaceuticals operates state-of-the-art manufacturing facilities equipped with cutting-edge technology and adheres to Good Manufacturing Practices (GMP) to ensure the production of safe and effective medications.
Ultima Pharmaceuticals offers a diverse range of pharmaceutical products that cater to a wide spectrum of medical needs. Their product portfolio includes medications for various therapeutic areas, such as cardiovascular health, respiratory disorders, gastrointestinal conditions, musculoskeletal disorders, dermatology, and many more.
One of the key aspects that sets Ultima Pharmaceuticals apart is its focus on continuous research and development. The company invests significantly in exploring new molecules, drug formulations, and delivery systems to improve treatment outcomes and patient experience. By staying at the forefront of medical advancements, Ultima Pharmaceuticals strives to provide innovative solutions that address unmet medical needs.
In addition to its commitment to product quality and innovation, Ultima Pharmaceuticals is dedicated to the well-being of its customers. The company ensures that its medications are affordable and accessible to people from all walks of life, regardless of their geographical location or economic background. This commitment to affordability and accessibility helps Ultima Pharmaceuticals make a positive impact on global healthcare.
Ultima Pharmaceuticals also prioritizes environmental sustainability and social responsibility. The company implements eco-friendly practices in its manufacturing processes and actively contributes to initiatives that benefit the local communities in which it operates. By adopting a holistic approach to business, Ultima Pharmaceuticals aims to create a positive and lasting impact on society as a whole.
Overall, Ultima Pharmaceuticals is a reputable pharmaceutical company that combines scientific expertise, technological advancements, and a strong commitment to improving healthcare. With its focus on quality, innovation, affordability, and social responsibility, Ultima Pharmaceuticals continues to make significant contributions to the global pharmaceutical industry.
What is Proviron?
Proviron is the brand name of Mesterolone which was developed medically to treat hypogonadism in men which causes low testosterone. Although it is sometimes loosely considered to be an AAS (androgen and anabolic steroid), it contains little anabolic capacity and so has only weak anabolic benefits.
Mesterolone (Proviron) Structure
Proviron Dosage
Many people make mistakes when planning a Proviron dosage simply because they don’t understand how it works or what it should be used for. Knowing exactly how Proviron can benefit you when you are using other steroids will make it possible to take the right dose and to get the best results from Proviron.
Beginner, Intermediate, and Advanced Proviron Dosage
Although Proviron is most commonly used by people who would be classed as advanced users – competitive bodybuilders – some people at the beginner level might still consider adding it to a cycle to evaluate results. There is little risk in doing so and since Proviron is quite effective when used for short periods, provides a good introduction to how to use an ancillary compound.
When used medically as an androgen replacement, Proviron is taken two to three times daily at a 25mg dose each time. This gives us a base dosage to work from when planning to use Proviron for bodybuilding purposes, but unlike many other types of steroids, the dosage rate does not increase dramatically for Proviron when compared to its medical use.
Taking the same or similar dose as is medically prescribed for androgenic treatment is still highly effective for bodybuilders. A daily dose of between 50mg per day at a minimum, up to 150mg per day maximum is more than sufficient for the mitigation of estrogen-related effects like water retention.
Regardless of experience level, Proviron is included in a cycle mainly to mitigate the estrogenic effects of other steroids. This means that your dosage of Proviron is going to heavily depend on which other compounds you’re using.
All experience levels from beginners right up to advanced users will want to stay within the same dosage range for Proviron, with 50mg daily being the minimum dose and 150mg daily as the maximum. Even though Proviron is considered quite safe up to 250mg per day, going beyond 150mg each day comes with little to no increased benefits but a higher risk of negative side effects, and such high doses are only considered by the most advanced and competitive of users.
Proper Proviron Administration and Timing
Proviron comes in 25mg tablets so your daily dosage is made up of 25mg increments. If taking 3 tablets daily for a 75mg dose, it’s recommended to spread the administration out throughout the day and not to take all three tablets at once because the compound has an active life of just 8 to 12 hours so regular administration is needed to maintain optimal blood levels.
The manufacturer of the original Proviron states that the tablets can be taken either with or without food, but that it is ideal to take the tablets as close to the same time each day as possible so your circulating levels of Proviron are maintained as efficiently as possible.
The timing of your Proviron administration will completely depend on the purpose of your use: do you want to use it throughout a steroid cycle for estrogen mitigation as a mild aromatase inhibitor compound, or are you looking for some hardcore physique hardening effects at the pre-contest stage?
It’s very common for competitive bodybuilders to use Proviron at higher doses of 150mg and sometimes more at the stage of being close to a contest. This allows androgens to quickly increase and a very hard, solid, and dry look can be achieved in this final stage, especially if lower androgenic cutting steroids like the Anavar cycle and Winstrol cycle have been used to get you lean and cut combined with a serious calorie-controlled diet. Those who are not already very lean near the end of a cutting cycle will see fewer benefits from Proviron. Body fat should be considerably low at this point, allowing Proviron to take hold to exert its fluid removal and hardening effects. Without a very lean and cut physique, these effects will be difficult to notice.
Female Proviron Dosage
Even though the risks of females using Proviron are well known, some women still choose to use it to gain physical enhancements. In these cases, a low dose and limited cycle length are critical to minimize virilization side effects. Females should not exceed 25mg daily of Proviron with a cycle length of no more than 5 weeks. Many females will still find virilization is still an issue at this low level of Proviron usage simply because it is a strong androgen and a DHT-derived compound whose androgenic side effects can not be mitigated through the use of any anti-androgenic drugs.
Proviron Cycles
Proviron is rarely used as a regular steroid in a cycle because it does not have strong anabolic effects that can contribute to either gaining muscle or fat loss. Where it is mostly used is as a type of helper compound during a steroid cycle where other steroids are being used as the main anabolic agents.
Proviron’s anti-estrogen ability helps mitigates some of the estrogenic activity of other steroids while contributing to goals like gaining a hardened physique, once again because of the anti-estrogen qualities that help reduce water retention. Below are some of the example cycles where Proviron can be included for great benefits:
Beginner Proviron Cycle
Beginner steroid users will almost always be starting with a testosterone compound and this is where you will include Proviron for added benefit. In any case, using Proviron alone is never recommended nor beneficial, due to its suppressive effects and its lack of ability to deliver truly desirable results as a standalone compound.
So as a beginner, you can safely add Proviron to your existing testosterone cycle at 50mg daily and expect to see some impressive hardening effects, as well as an increase in the effectiveness and results from the testosterone itself as more of it is freed up while Proviron binds to the SHBG protein.
As Proviron is generally very liver safe despite being an oral, you can use it for a full testosterone cycle although many people will select to only use it for a short period towards the end of the cycle.
Intermediate Proviron Cycle
Any level of user will see good results even at the 50mg daily level with Proviron and for many intermediate users, this can be as far as you want to take it. However, it will largely depend on what steroids are being used in your cycle and whether your main goal is for maximum muscle hardness or to use Proviron mainly to mitigate estrogenic side effects.
Stacking with your regular testosterone cycle will provide highly beneficial for the intermediate user as you will gain the great benefit of increased testosterone being available in the bloodstream while Proviron binds to SHBG. If your goal with Proviron is to inhibit aromatization then it’s safe to use this compound for a 12-week cycle if desired.
Advanced Proviron Cycle
The most advanced steroid users should still not exceed 150mg daily of Proviron. Most advanced users will likely be aiming to use Proviron to provide a last-minute hardening boost near the end of an intense cutting cycle or as pre-contest preparation.
The advanced user will already be significantly lean and cut and will have controlled water retention well during a cutting phase that makes use of compounds like Clenbuterol, testosterone, Winstrol, and Anavar. In this scenario, the advanced user will benefit greatly from Proviron’s additional reduction in the fluid build-up towards the end of the cycle.
Stacking Proviron
Proviron can be stacked with just about any anabolic steroid but its best use is when you combine it with other steroids commonly used in a cutting cycle. These include Masteron, Anavar, Trenbolone and Winstrol.
Whichever compounds you’re using, Proviron will provide the greatest benefit alongside them at the 100-150mg daily range. There are two main ways to include Proviron in your cutting cycle: for a very short time near the end of the cycle to promote increased hardening, or for a longer duration of 8 weeks during the cycle, with a maximum of 12 weeks still considered effective.
Proviron Results
Anyone considering using Proviron should know that this is not a bulking steroid. Not all steroids are beneficial for gaining mass and this one falls into another category in terms of its usefulness. This is a steroid that is rarely used to give you direct results itself, but instead to work with the other compounds you’re using in what is known as an ancillary compound.
So the results from Proviron, when combined with other steroids, are focused on:
Minimizing and combating the effects of estrogen
As a result of rising estrogen levels through the use of other aromatizing steroids like testosterone, Proviron can help slow or even halt these other steroids from aromatizing which prevents conversion to estrogen. This is achievable even at a low dose of 50mg each day which can greatly help reduce or hold off the gynecomastia and fluid retention caused by other aromatizing steroids. The result is a physique that is noticeably harder and drier – exactly what is required in a cutting and contest preparation phase.
Enhances the effects of other steroids
By binding with SHBG your levels of free and available testosterone are increased which in turn boosts the effects of other steroids being used. The level of hardness you can achieve with other cutting steroids is also enhanced with Proviron, particularly with compounds like Winstrol, Anavar, and Masteron.
PCT Compound
Another potential use for Proviron is as a PCT compound but it is generally not recommended and can be a common mistake made by beginners in selecting this compound for PCT because of its known anti-estrogen qualities.
While that is desirable, the downside is that Proviron still causes some testosterone suppression and no matter how mild, this is exactly the opposite of what we need during PCT. So your expected results if using Proviron for PCT are not going to be anywhere as impressive and effective as you’ll see when using the standard PCT drugs of choice like Nolvadex or Clomid which are often combined with hCG.
Proviron Side Effects
Proviron is not an aromatizing steroid so doesn’t come with estrogenic side effects. More than that, it does have the ability to affect the aromatase enzyme in a way that can bind to it and inhibit its activity, giving Proviron some measure of aromatase inhibition or anti-estrogen effect.
While this isn’t anywhere near as powerful as a true aromatase inhibitor, it is a welcome attribute of a steroid when so many other steroids display the very opposite effects. However, while estrogen-related side effects aren’t an issue with Proviron itself, there are other potential side effects to be aware of.
Androgenic side effects: Proviron has some strong androgenic effects, after all, it was originally made to medically treat deficiencies in androgen. It is based on DHT which itself is an androgen so it should come as no surprise that you can expect to see activity in this area and these side effects cover issues that most steroid users will be familiar with, including potential acne and hair loss or male pattern baldness.
The occurrence and severity of these particular side effects are highly individual and some people may experience very little or none at all, while others will see quite severe flare-ups of acne. When it comes to hair loss, if you’re genetically predisposed to baldness then Proviron can stimulate this to happen much earlier than it might otherwise have done so. Guys without any genetic links to hair loss won’t have to worry about this androgenic side effect.
The high androgenic activity in Proviron makes it unsuitable for use by females as it’s almost certain to cause an onset of masculine features like a deeper voice and body hair growth. Proviron is an even higher risk for females when it comes to these side effects compared with some other steroids and therefore Proviron is not recommended to be used by females.
Another area that raises concerns with Proviron use is that of cholesterol and compared with many other steroids which themselves can cause some serious impacts on cholesterol, Proviron is considered one of the more harsh ones in this regard and one that comes with a high risk to cholesterol health.
For this reason, anyone with existing high cholesterol issues is always advised to avoid using Proviron at all. Even those with normal cholesterol levels will need to remain alert to what effect Proviron is having on your cholesterol throughout your cycle.
There’s no doubt that Proviron can have a very strong impact on your good cholesterol levels, potentially reducing them by almost a third in some cases. At the same time, it can be raising your bad cholesterol levels by a significant amount.
Without sustained cholesterol-friendly diet habits and cardio exercise, while you’re using Proviron, it does pose a very high risk in this area so anyone wanting to use Proviron absolutely must formulate a plan to help maintain healthy cholesterol for the duration of the cycle.
As you might expect, Proviron also comes with the side effect of testosterone suppression but its impact is quite minimal when compared to almost any other steroid. At the dose that most guys will be using Proviron, is unlikely to cause any noticeable testosterone suppression-related side effects, and therefore it is one of the very few steroids you can use in most cases without the need for adding a testosterone steroid.
Proviron Post Cycle Therapy
While Proviron itself comes with minimal or even no noticeable testosterone suppression at doses that are effective for performance enhancement, almost everyone will use this steroid with other compounds that do suppress natural testosterone production. Therefore a PCT plan will still almost always be required to get your normal testosterone function stimulated again and to avoid falling into a state of low testosterone where muscle loss and fat gain occurs, among other serious symptoms.
Proviron itself is sometimes utilized in PCT since one of its medical uses is to enhance fertility. By using Proviron in PCT to reduce estrogen, the recovery of testosterone might be improved but this needs to be weighed up with Proviron’s tendency to mildly reduce natural testosterone
So while some people might choose to use Proviron during PCT because they can’t access other better PCT drugs like SERMs, it is generally not advisable for the best results.
Proviron FAQs
Is Proviron toxic to the liver?
Unlike many other oral steroids, Proviron does not come with the risk of liver toxicity. That’s because Proviron is not a 17 alpha-alkylated anabolic-androgenic steroid (17alpha-AAS) and it is only oral steroids in that category that come with a very high risk of hepatotoxicity and liver damage. But since you will almost certainly be using other steroids in your cycle, some of which might come with their toxic effects on the liver, this is an issue that should always be considered when using any steroid.
Is Proviron safe?
All steroids come with their risks, especially when they are misused by using them in very high doses or for extended periods. Proviron is considered one of the safest steroids available with relatively mild side effects compared with many more powerful steroids. Even though Proviron is an oral steroid, it does not cause damage to the liver which is another reason this steroid is thought to be one of the least harmful.
Where can I buy Proviron?
Even though Proviron is not one of the most popular steroids out there, locating it for purchase is not that difficult. This includes pharmaceutical grades from the original creator Schering, plus products from underground labs. The lab products need to be bought with caution as fakes do exist as do low-quality inferior products.
If you can get pharmaceutical grade Proviron this is the most ideal option. Even though Proviron is not technically an anabolic steroid, it is still treated as such in most countries and is not legal to purchase or use without a prescription.
Should I take Proviron during my cycle?
Proviron is used for specific purposes during a steroid cycle and only if you understand what it can do and whether you will benefit from it should you then decide whether to include Proviron during your cycle. While it is possible and entirely safe to include Proviron during an entire 8, 10, or even 12-week cycle with other steroids, just doing so without understanding why will bring you no benefits.
For many people, Proviron’s greatest power is in its excellent hardening effects and for many people, it might only be necessary to include Proviron in the final couple of weeks of a cycle rather than for the entire cycle. Exactly how and when you use Proviron during your cycle should be a decision made based on your own goals and the potency of other steroids being used.
Does Proviron block estrogen?
Proviron acts as a mild aromatase inhibitor so by that nature it has some estrogen block effect. It needs to be known though that you won’t find this estrogen-blocking effect as strong as it is with true AI drugs like Arimidex, it does come with great benefits for steroid users because increased estrogen is the cause of gyno and water retention, so Proviron can greatly help combat these, leading to increased muscle hardness with a low concentration of estrogen in the blood.
Is Proviron used for cutting?
Proviron can play a very beneficial role in cutting phases. It can enhance physique hardness which comes along with mitigating estrogen, as it’s the estrogenic effects of steroids that bring about water retention and that bloated look we all want to avoid.
With its anti-estrogen activity, Proviron can offset this and help you retain a much harder, drier look which is why it's most often used for cutting purposes. Proviron itself can also contribute to hardening but the most power lies in its ability to amplify the hardening effects that you gain from other steroids and that’s why it’s often included near the end of a cycle rather than used throughout the entire cycle.
Is Proviron suppressive?
Proviron does not have a powerful suppressive effect on natural testosterone function. It can cause some mild suppression but nowhere near the level of many other steroids which can often shut down testosterone function completely.
At a reasonable dose that does not exceed 150mg daily, the suppressive effects of Proviron are unlikely to be noticed by most users. However since almost everyone will use Proviron with other steroids that do cause much more severe suppression, that will still likely need to be dealt with both during and after your steroid cycle.
My Conclusion and Recommendation
Proviron has several very useful functions for bodybuilders and anyone serious about physique enhancement, including for contests. It can reduce the fluid build-up caused by other steroids because of its anti-estrogen properties. It can help free up circulating testosterone by binding to the protein that otherwise has testosterone binding to it.
Proviron is very useful as both a mild and effective aromatase inhibiting compound during a cycle, or to use as a powerful last-minute hardener towards the end of a hardcore cutting cycle where fluid retention needs to be at the lowest possible level.
cJC-1295 (without DAC) is a synthetic peptide that is a modified form of the growth hormone-releasing hormone (GHRH). It belongs to a class of compounds known as growth hormone secretagogues (GHS), which stimulate the release of growth hormone (GH) from the pituitary gland.
Unlike the original cJC-1295 peptide with DAC (Drug Affinity Complex), the cJC-1295 variant without DAC has a shorter half-life. This means that it gets cleared from the body more quickly, resulting in a more rapid onset of action and a shorter duration of effect.
The primary function of cJC-1295 (without DAC) is to increase the production and release of growth hormone in the body. Growth hormone plays a crucial role in various physiological processes, including growth, metabolism, and tissue repair. By enhancing GH secretion, cJC-1295 (without DAC) can promote muscle growth, improve body composition, increase energy levels, and enhance recovery from injuries or intense physical activities.
One of the key benefits of cJC-1295 (without DAC) is its ability to promote sustained GH release over an extended period. This is attributed to its resistance to degradation by enzymes called proteases, which allows it to remain active in the body for a longer duration compared to natural GHRH. As a result, cJC-1295 (without DAC) offers a more stable and consistent elevation of GH levels, which can be advantageous for individuals seeking long-term effects.
It's worth noting that cJC-1295 (without DAC) is typically administered through subcutaneous injections. The recommended dosage and frequency may vary depending on the individual's goals, response, and other factors. It is important to consult with a healthcare professional or a qualified medical practitioner before using cJC-1295 (without DAC) or any other peptide.
As with any medication or peptide, cJC-1295 (without DAC) may have potential side effects or interactions with other substances. Some common side effects associated with growth hormone secretagogues include headaches, flushing, dizziness, and increased hunger. It is essential to be aware of these potential risks and to use cJC-1295 (without DAC) under the guidance of a healthcare professional.
Please note that the information provided here is for informational purposes only, and it is not intended to replace professional medical advice.
Hexo Trenbolone 100mg/ml is a powerful and widely used anabolic steroid that is popular among bodybuilders and athletes. It belongs to the family of synthetic steroids known as trenbolones, which are derivatives of the hormone nandrolone.
Hexo Trenbolone is known for its exceptional anabolic properties, meaning it promotes muscle growth and aids in the development of lean muscle mass. It is highly regarded for its ability to enhance strength and performance, making it a preferred choice for athletes and individuals looking to improve their physical performance.
One of the key features of Hexo Trenbolone is its high affinity for androgen receptors, which allows it to activate these receptors more effectively than other anabolic steroids. This leads to increased protein synthesis, nitrogen retention, and enhanced red blood cell production, resulting in significant muscle growth and improved endurance.
Hexo Trenbolone is also known for its ability to promote fat loss. It increases the body's metabolic rate, making it easier to burn excess body fat while preserving lean muscle tissue. This makes it an ideal choice for individuals in cutting phases or those aiming to achieve a lean and ripped physique.
It is important to note that Hexo Trenbolone is a highly potent steroid and should be used with caution. The recommended dosage for male users typically ranges from 200-400mg per week, divided into two or three injections. Female users are advised to avoid using Hexo Trenbolone due to its strong androgenic properties.
Like all anabolic steroids, Hexo Trenbolone carries potential side effects, including increased aggression, acne, oily skin, hair loss, and suppression of natural testosterone production. It is crucial to use Hexo Trenbolone responsibly and to follow recommended dosage guidelines to minimize the risk of adverse effects.
In conclusion, Hexo Trenbolone 100mg/ml is a potent anabolic steroid that is highly effective in promoting muscle growth, improving strength, and enhancing performance. However, it should be used responsibly and under the guidance of a medical professional to ensure the best results and minimize potential side effects.
HCG stands for Human Chorionic Gonadotropin, which is a peptide hormone naturally produced by the placenta during pregnancy. It is primarily known for its role in supporting pregnancy and fertility. However, HCG has also gained popularity as a supplement in various fields such as weight loss, bodybuilding, and hormone therapy.
HCG is composed of two subunits, an alpha subunit and a beta subunit. The alpha subunit is similar to other hormones in the body, while the beta subunit is specific to HCG. It is the beta subunit that gives HCG its unique properties and functions.
During pregnancy, HCG plays a crucial role in maintaining the production of other hormones, such as progesterone and estrogen, which are essential for the development of the fetus. It helps to sustain the corpus luteum, a temporary gland that produces these hormones until the placenta takes over the role later in pregnancy.
In the medical field, HCG is widely used to treat infertility in both men and women. In women, it stimulates ovulation, which can help with fertility issues. In men, it can increase testosterone production and improve sperm count and quality.
Outside of medical applications, HCG has gained popularity as a weight loss aid. It is often used in combination with a very low-calorie diet (VLCD). HCG is believed to help suppress appetite, promote fat burning, and preserve muscle mass during calorie restriction. However, the effectiveness of HCG for weight loss is a topic of debate, and more research is needed to establish its true efficacy.
In the realm of bodybuilding and athletic performance, HCG is sometimes used to restore natural testosterone production after a cycle of anabolic steroids. This is because anabolic steroid use can suppress the body's natural testosterone production, and HCG can help kickstart the process of restoring normal hormone levels.
It's important to note that the use of HCG as a supplement should be done under the guidance of a healthcare professional. They can provide appropriate dosages, monitor any potential side effects, and ensure its safe use.
Overall, HCG is a peptide hormone with diverse applications in medicine, fertility treatments, weight loss, and athletic performance. While it has shown promising results in certain areas, more research is needed to fully understand its benefits and risks in different contexts.
CHARACTERISTICS
ACTIVE HALF-LIFE
9 HOURS
CLASSIFICATION
STEROIDAL AROMATASE INHIBITOR
DOSAGE
12.5-25 MG/DAY
ACNE
NO
WATER RETENTION
NO
HBR
NO
HEPATOTOXICITY
NO
AROMATIZATION
NO
ACTIVE SUBSTANCE
FORM
30 TABS X 25 MG
MANUFACTURER
RX Pharmaceuticals
DESCRIPTION
AROMASIN 25mg
50 tabs x 25mg
Exemestane is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin. In fact, the Aromasin brand name is the only pharmaceutical grade brand of the Exemestane AI due to the tight patent Upjohn has maintained on the product. While tightly controlled by the pharmaceutical giant, Aromasin is available in numerous countries around the globe. Aromasin was first released on the U.S. market in 2000 after shortly gaining FDA approval a few months prior in 1999. The primary purpose of use as with most AI’s would be to combat breast cancer in post-menopausal women. Shortly after, the AI would begin to gain a lot of popularity among anabolic steroid users for its ability to protect against estrogenic related side effects. This action is very similar to the older and more popular AI’s in Arimidex (Anastrozole) and Femara (Letrozole). It would also gain a fair amount of popularity in Post Cycle Therapy (PCT) plans among steroid users. It was not the first AI to gain such popularity but would prove to be a little more advantageous for this purpose than most AI’s.
Aromasin Functions & Traits:
Aromasin is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to estrogen. Aromasin has the ability to block aromatization, which in turn inhibits the production of estrogen, and thereby lowers the body’s serum estrogen levels. This will prove useful to breast cancer patients as breast cancer often feeds off the estrogen hormone. It will also prove useful to the anabolic steroid user. Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process, specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature. A prime example would be Nandrolone, which while it aromatizes only does so at 20% the rate of testosterone. However, it also carries a strong progestin nature, and progesterone has been well noted for carrying the ability to stimulate the estrogenic mechanism in the mammary tissue. By administering Aromasin during the use of anabolic steroids, this will inhibit the aromatase process, lower estrogen levels and protect the individual from estrogenic side effects. How effective is Aromasin? The product claims on average to have the ability to lower serum estrogen levels by 85%. Aromasin also has the ability to stimulate natural testosterone production, which is precisely why some will include it during their PCT. Like Arimidex and Letrozole, Aromasin will stimulate the pituitary to release more Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), two hormones essential to natural testosterone production. While the other common AI’s share this trait, Aromasin has been shown to carry a slight androgenic effect, as well as the ability to increase the production of Insulin-Like Growth Factor-1 (IGF-1). This is a trait no other AI can claim to carry. By using Aromasin during PCT, the individual receives the desired testosterone boost necessary for recovery, but with the IGF-1 increase also creates a stronger anabolic atmosphere. This is deemed useful by some steroid users as it could potentially give them the ability to protect their lean tissue all the more during use. However, when we look at the direct effects of Aromasin as it pertains to PCT, we will find PCT use is normally not recommended despite these positive effects.
Effects of Aromasin:
In a therapeutic setting, by blocking the aromatase enzyme, Aromasin actively prohibits the cancer from feeding off the hormone necessary to its survival. It has been proven highly effective for this purpose, but only after the use of the Selective Estrogen Receptor Modulator (SERM) Nolvadex (Tamoxifen Citrate) has failed. While effective, it is also not as commonly used as Arimidex for this purpose as Arimidex largely maintains itself as the primary AI in breast cancer treatment not only among post-menopausal women but in a host of breast cancer scenarios. Then we have Aromasin as an anti-estrogen for the anabolic steroid user. By understanding its functions and traits you should already understand the effects of Aromasin in this regard. Excess estrogen levels can promote gynecomastia and water retention and possibly high blood pressure as a secondary issue. However, keep in mind such effects are not possible with all anabolic steroids, primarily it must carry an estrogenic nature, it must be able to aromatize to lead to such effects or carry a progesterone nature. Testosterone is the primary aromatizing steroid, but testosterone derived steroids like Dianabol can also promote strong estrogenic action. Then we have the Boldenone (Equipoise) hormone, and while it only aromatizes at 50% the rate of testosterone, this is still enough to cause an estrogen buildup in some. Finally, we’re left with 19-nortestosterone (19-nor) anabolic steroids. 19-nor compounds will primarily include all forms of Nandrolone and Trenbolone. As discussed Nandrolone aromatizes at 20% the rate of testosterone, but it also carries a very strong progestin nature. This can promote a fair amount of estrogenic activity in many men. As for Trenbolone, it does not aromatize at all, but its moderately strong progestin nature can make gynecomastia a possibility depending on the individual’s sensitivity. When use is coupled with an aromatizing steroid, this will greatly enhance the odds of gynecomastia. Regardless of the steroid in question, Aromasin can offer protection from the estrogenic effects. An important note: Aromasin will have no affect on dihydrotestosterone (DHT) derived anabolic steroids as they do not convert to estrogen. Such steroids cannot lead to gynecomastia or excess water retention; it is impossible. The exception would be Anadrol (Oxymetholone), while a DHT derivative, it carries with it a strong estrogenic nature. However, while estrogenic action is present, the hormone does not aromatize, meaning there is no aromatization for Aromasin to inhibit. The use of an AI will not affect the estrogenicity of Anadrol. For protection from such a steroid, the individual will need to inhibit activation of the estrogenic mechanism, and this will make SERM’s the first line of defense. The final effects of Aromasin surround its use in a PCT plan. Due to the use of anabolic steroids natural testosterone production is suppressed. The rate of suppression will be dependent on the steroids being used, and to a degree, the total doses, but natural production will be suppressed nonetheless. Most male steroid users are advised to include exogenous testosterone in all their cycles in order to ensure they have enough testosterone to meet their body’s needs. This won’t be an issue for most men as testosterone is normally a base steroid in a cycle. If it is not used as a base steroid the individual should ensure he administers the minimal amount necessary to combat suppression. Once the cycle of steroids is over, while exogenous testosterone protected the individual while on cycle, at the end of the cycle natural production is still suppressed. Natural production will begin again once all the exogenous hormones have cleared the system, but returning to your prior levels pre-cycle will take a lot of time. In fact, it could potentially take up to a year assuming no other anabolic steroids were used during this period. By implementing a PCT plan, we stimulate natural testosterone production, cut down on the total recovery time and ensure we have enough testosterone for proper bodily functions. This does not bring our total levels back to their previous naturally high state, but it speeds up the recovery and ensures we do not spend a lot of time in a low testosterone state. Not only is a low testosterone condition extremely unhealthy and bothersome due to a host of possible symptoms, it can see the lean tissue gained on cycle destroyed. During a phase of low testosterone, it is easy for cortisol to become dominant in the body, which will destroy muscle tissue and promote fat gain. Due to the need for a strong PCT and Aromasin carrying extremely strong natural testosterone stimulating properties, this makes it very appealing for this purpose. Due to the slight androgenic nature and moderately decent promotion of IGF-1 this makes it even more appealing. However, we must consider the primary purpose of Aromasin, which is as an anti-estrogen. High levels of estrogen can be problematic, but the hormone is still necessary to our body’s health. It is important in maintaining a proper immune system, as well as in the maintenance of healthy cholesterol levels. Then consider the PCT, which in part is primarily designed to stimulate natural testosterone production, but the overall primary point is to normalize the body. We cannot normalize with low estrogen levels. For a proper PCT that not only stimulates testosterone production but promotes overall normalization, SERM’s should always be your first choice.
Side Effects of Aromasin:
The possible side effects of Aromasin are very similar to the primary AI’s in Arimidex and Letrozole. Many who use the AI often report fatigue and weakness, but this is often not an issue for the anabolic steroid user. The exception would be the steroid user who is in the middle of a harsh cutting cycle, such as in preparation for a bodybuilding contest. Many bodybuilders often report strong lethargy during this period, which isn’t surprising due to the intense diet and often incredible amount of cardio. However, it’s often amplified by the use of an AI like Aromasin. Overall, the primary possible side effects of Aromasin include:
- Weakness or Fatigue
- Headaches
- Hot Flashes
- High Blood Pressure
- Joint Pain
- Depression (rare)
- Nausea and/or Vomiting (rare)
While the above represents the primary possible side effects of Aromasin, studies have shown the AI may have the ability to decrease bone mineral content, which in turn could increase the individual’s risk of osteoporosis. This should not be a large concern for most steroid users as many steroids actually have the ability to greatly increase bone mineral content. Regardless, when looking at the side effects of Aromasin, while they largely revolve around possible the overall chance surrounds the individual’s nature. We all respond to varying medications and hormones differently. This includes AI’s like Aromasin to every last over the counter medication on earth and even applies to many of the foods we eat. The final side effect of Aromasin will revolve around cholesterol. Aromasin, like all AI’s has the ability to negatively skew cholesterol levels. Alone it doesn’t appear to carry this ability at a significant level, but when combined with an aromatizing steroid data shows that it may in fact become significant. This can be an issue of concern for the steroid user as many anabolic steroids already have the ability to negatively affect cholesterol levels. This is an issue that many steroid users give very little attention to. Most are far more concerned with possible visually related side effects such as acne, possible hair loss and water retention, but these really aren’t too concerning. Cholesterol, that is an issue of concern, and while it is very possible for a healthy adult to maintain proper cholesterol levels and use anabolic steroids, it will take some effort and is worthy of your attention. When looking at the hard data at hand, we find that the use of Testosterone at a therapeutic level, such as in the treatment of low testosterone will statistically produce no negative effect on cholesterol levels. However, the same data shows that when the same level of testosterone is conjoined with an AI like Aromasin, HDL cholesterol can be decreased or suppressed by as much as 25%. Then we have performance level doses, which will have a moderate effect on HDL cholesterol, but once again this is exasperated by the use of an AI. Due to the potential negative effect on cholesterol, Aromasin and other AI’s should only be used when necessary. Many anabolic steroid users rely on AI’s heavily and that is a mistake. It is possible to avoid estrogenic side effects without an AI. It’s not always possible, but when possible it should be avoided. Many will find SERM’s like Nolvadex to provide all the protection they need. A SERM will not inhibit aromatization or lower serum estrogen levels, but it will attach to the receptors and prevent estrogen from binding. This can greatly aid in the prevention of gynecomastia. It can help with water retention to a degree, but it’s often not enough for many men. However, most men will find they can do a lot to control water retention if they do a better job controlling their diets. Excess calories are necessary for growth, but when the excess is heavy this will promote water retention. This will hold very true with excess carbohydrates more so than anything else and will hold true with or without the use of anabolic steroids. If the individual is consuming an abundant amount of calories and adds an aromatizing steroid to the mix, this will only exasperate the problem. Further, keep in mind that while excess calories are necessary for growth, normally this only requires a slight increase above maintenance. The total increase will vary from one man to the next based on his need, but rarely is it as abundant as many make it. Control your diet and your carbohydrate intake and you will do a lot for controlling water retention. While SERM’s can offer a lot of protection, some will still need AI’s. This will be very true in many hardcore plans, and can often be beneficial to a contest cycle. However, use should be limited to when only necessary. Many who implement moderate anabolic steroid cycles, which is the vast majority of anabolic steroid users would be surprised by how little Aromasin or any AI they could actually get by with.
Testosterone Cypionate is a synthetic form of the male hormone testosterone. It is an injectable medication that is primarily used to treat conditions caused by low levels of testosterone in men. Testosterone is a crucial hormone responsible for the development and maintenance of male sexual characteristics, muscle mass, bone density, and overall well-being.
Testosterone Cypionate is classified as an androgen and anabolic steroid, meaning it not only promotes the development of secondary sexual characteristics but also enhances muscle growth and strength. It is often prescribed to individuals who have a medical need for testosterone replacement therapy (TRT), such as those with hypogonadism or delayed puberty.
When administered intramuscularly, Testosterone Cypionate is slowly released into the bloodstream over a period of several days. This prolonged release allows for less frequent injections compared to shorter-acting testosterone preparations. Typically, injections are given every 1-2 weeks, depending on the individual's specific needs and response to treatment.
In addition to its medical uses, Testosterone Cypionate is sometimes abused by athletes and bodybuilders to enhance performance and increase muscle mass. It is worth noting that such use is illegal and carries potential health risks.
Like any medication, Testosterone Cypionate may have side effects. Common side effects include acne, oily skin, increased body hair growth, fluid retention, and changes in mood or libido. More serious side effects can occur, such as liver toxicity, cardiovascular problems, and hormonal imbalances, particularly with long-term or excessive use. It is important to use this medication under the guidance of a healthcare professional and follow the prescribed dosage and administration instructions.
Before starting Testosterone Cypionate therapy, individuals should undergo a thorough medical evaluation, including a blood test to assess testosterone levels. This ensures that treatment is tailored to each person's specific needs and helps monitor the effectiveness of therapy over time.
Overall, Testosterone Cypionate is a widely used medication for testosterone replacement therapy in men with low testosterone levels. It helps restore and maintain hormonal balance, leading to improvements in various aspects of health and well-being. However, it should be used responsibly and only under the supervision of a healthcare professional.
Tadalafil: A Detailed Description
Introduction:
Tadalafil is a medication primarily used to treat erectile dysfunction (ED) and symptoms of benign prostatic hyperplasia (BPH). It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Marketed under the brand name Cialis, tadalafil has gained popularity as a reliable and effective treatment option for men facing sexual health issues. This article aims to provide a detailed description of tadalafil, including its mechanism of action, therapeutic uses, dosage, side effects, and precautions.
Mechanism of Action:
Tadalafil works by inhibiting the enzyme PDE5, which is responsible for breaking down cyclic guanosine monophosphate (cGMP). Inhibition of PDE5 leads to increased levels of cGMP in the smooth muscle cells of the penis, causing relaxation of the blood vessels and improved blood flow. This enhanced blood flow helps in achieving and maintaining an erection during sexual stimulation.
Therapeutic Uses:
1. Erectile Dysfunction (ED): Tadalafil is primarily prescribed to treat ED, a condition characterized by the inability to achieve or sustain an erection sufficient for sexual intercourse. It is effective in treating both organic and psychogenic causes of ED, making it a versatile choice for individuals with different underlying causes.
2. Benign Prostatic Hyperplasia (BPH): Tadalafil is also approved for the treatment of BPH, a condition in which the prostate gland becomes enlarged, causing urinary symptoms such as frequent urination, weak urine flow, and difficulty emptying the bladder. By relaxing the smooth muscle of the prostate and bladder, tadalafil helps alleviate these symptoms.
Dosage and Administration:
Tadalafil is available in various strengths, including 2.5mg, 5mg, 10mg, and 20mg tablets. The recommended starting dose for most men is 10mg, taken orally before sexual activity. However, the dose can be adjusted based on individual response and tolerability. It is important to note that tadalafil should not be taken more than once in a 24-hour period.
For the treatment of BPH, a daily dose of 5mg tadalafil is usually prescribed. This lower dose can also be used for men with both ED and BPH, providing simultaneous relief for both conditions.
Side Effects:
While tadalafil is generally well-tolerated, it may cause some side effects in certain individuals. Common side effects include headache, facial flushing, indigestion, nasal congestion, and back pain. These side effects are usually mild and transient, resolving on their own without medical intervention.
Less common but more serious side effects may include sudden vision or hearing loss, chest pain, and priapism (a prolonged and painful erection). If any of these side effects occur, it is important to seek immediate medical attention.
Precautions and Contraindications:
Tadalafil should not be taken by individuals who are allergic to it or any of its components. It is also contraindicated in patients who are taking nitrates, as the combination can cause a potentially dangerous drop in blood pressure.
Caution should be exercised when using tadalafil in individuals with certain medical conditions, such as severe liver or kidney disease, cardiovascular disease, or a history of priapism. It is advisable to consult a healthcare professional before starting tadalafil to ensure its safety and appropriateness for individual circumstances.
Drug Interactions:
Tadalafil can interact with certain medications, including alpha-blockers, antihypertensives, and certain antibiotics or antifungals. These interactions can either increase or decrease the levels of tadalafil in the body, potentially leading to adverse effects or reduced efficacy. It is essential to inform healthcare providers about all medications being taken to avoid any potential interactions.
Conclusion:
Tadalafil, a PDE5 inhibitor, is a widely used medication for the treatment of erectile dysfunction and benign prostatic hyperplasia. It works by increasing blood flow to the penis, facilitating erections, and relieving urinary symptoms associated with BPH. With its effectiveness, convenience, and relatively mild side effect profile, tadalafil has become a popular choice for many men seeking treatment for their sexual health concerns. However, it is crucial to use tadalafil under the guidance of a healthcare professional, taking into consideration individual medical history, potential drug interactions, and appropriate dosage for optimal results and safety.
CHARACTERISTICS
ACTIVE HALF-LIFE
1 - 1.5 DAYS
CLASSIFICATION
ANABOLIC STEROID
DOSAGE
MEN 300-700 MG/WEEK
ACNE
YES
WATER RETENTION
NO
HBR
NO
HEPATOTOXICITY
LOW
AROMATIZATION
NO
ACTIVE SUBSTANCE
FORM
10 ML X 100 MG/ML
MANUFACTURER
Rx Pharmaceuticals
DESCRIPTION
MASTERON P 100 - XENO LABS
1 vial x 10 ml/100mg
Carrier: MCT Oil
Drostanolone Propionate is an anabolic androgenic steroid that first hit the market around 1970 under the trade name Masteron manufactured by Syntex. However, the compound was actually developed by Syntex in 1959 along with Oxymetholone (Anadrol) but would not be released until well after Anadrol. Syntex would also provide the compound under numerous other brand names such as Masteril and Metormon among others, as well as Drolban under the license given by Syntext to Lilly. However, Masteron has remained the most recognizable brand. As a therapeutic agent, Masteron enjoyed two decades of success in combating advanced inoperable breast cancer in postmenopausal women. It would also become a popular cutting steroid among bodybuilders, which is where Masteron is currently most commonly found. However, the original Masteron brand is no longer available; in fact, nearly every pharmaceutical brand on earth has been discontinued. This compound is still approved by the U.S. FDA, but it is rarely used in breast cancer treatment any longer in favor of other options. The steroid is, however, still tremendously popular in competitive bodybuilding cycles and often considered essential to contest preparation.
Masteron Functions & Traits:
Drostanolone Propionate is a dihydrotestosterone (DHT) derived anabolic steroid. Specifically, Masteron is the DHT hormone that has been structurally altered by the addition of a methyl group at the carbon 2 position, This protects the hormone from the metabolic breakdown by the 3-hydroxysteroid dehydrogenase enzyme, which is found in the skeletal muscle. It also greatly increases the hormone’s anabolic nature. This simple structural change is all it takes to create Drostanolone, and from here the small/short Propionate ester is attached in order to control the hormone’s release time. Drostanolone Enanthate can also be found through some underground labs, which does not have to be injected as frequently, but it is somewhat rare compared to the Propionate version. The majority of all Masteron on the market will be Drostanolone Propionate. On a functional basis, Masteron is well-known for being one of the only anabolic steroids with strong anti-estrogenic properties. Not only does this steroid carry no estrogenic activity, but it can actually act as an anti-estrogen in the body. This is why it has been effective in the treatment of breast cancer. In fact, the combination of Masteron and Nolvadex (Tamoxifen Citrate) has been shown to be far more effective than chemotherapy in the treatment of inoperable breast cancer in postmenopausal women. This also makes it a popular steroid among bodybuilders as it could actually prohibit the need for an anti-estrogen when used in the right cycle. This will also prove advantageous during the cutting phase due to the hardening effects it can provide. Masteron carries relatively low anabolic and androgenic ratings; however, these ratings are somewhat misleading. It’s important to remember DHT, the basis of Masteron, is five times more androgenic than testosterone with a much stronger binding affinity to the androgen receptor. This again promotes a harder look and can also enhance fat loss. Most all anabolic steroids are well-noted for enhancing the metabolic rate, but strong androgens have a tendency to directly promote lipolysis. As an anabolic, Masteron isn’t well-known for promoting gains in lean muscle mass. It has never been used for muscle wasting in a therapeutic sense and will almost always be found in cutting plans among performance athletes. It can, however, promote significant boosts in strength, which could prove beneficial to an athlete who may not necessarily be looking for raw mass.
Effects of Masteron:
Without question, the effects of Masteron will be displayed in the most efficient way during a cutting cycle. However, for the effects to be truly appreciated the individual will need to be extremely lean. This is why the hormone will most commonly be found at the end of bodybuilding contest prep cycles as the individual should already be fairly lean at this stage. The added Masteron will help him lose that last bit of fat that often hangs on for dear life at the end of a cycle. It will also ensure his physique appears as hard as can be. Of course, the anti-estrogenic effect will simply enhance this overall look. For those that are not competitive bodybuilder lean, it is possible that the effects of Masteron may not be all that noticeable. The individual who is under 10% body fat should be able to notice some results and produce a harder, dryer look, but much over 10% and the effects may not be all that pronounced. As a potent androgen, Masteron can benefit the athlete looking for a boost in strength. This can be a very beneficial steroid for an athlete who is following a calorie restricted diet in an effort to maintain a specific bodyweight necessary for his pursuit. The individual could easily enjoy moderate increases in strength and a slight improvement in recovery and muscular endurance without unwanted body weight gain. As a bulking agent, the effects of Masteron will prove to be rather week. It is possible the hormone could provide gains in mass similar to Primobolan Depot, which won’t be that strong either, if the total dose was high enough. However, the relative gain in size will be very moderate with many anabolic steroids being far more suited for this period of steroidal supplementation. There are those who may wish to include Masteron in a bulking plan for its anti-estrogenic and fat loss effects. The latter would ensure they kept their body fat gain minimized during off-season bulking phases, but this isn’t reason enough to use it in this phase. Body fat should be controllable without it. As for the anti-estrogenic effects, off-season cycles are normally comprised of large amounts of aromatase activity due to high doses of testosterone. Progesterone activity is also commonly high with the addition of Nandrolone compounds and possible Trenbolone. Consider additional Anadrol or Dianabol and this estrogenic activity can become very pronounced. Unfortunately, while possessing anti-estrogenic effects, Masteron will not be strong enough to combat this level of estrogenic activity.
Side Effects of Masteron:
In many ways, Masteron is a fairly side effect friendly anabolic steroid. Side effects of Masteron use most certainly exist, but most men will find this steroid highly tolerable. As for females, virilization symptoms can be strong with this steroid, but we will also find they can be managed with the right plan. In order to understand the side effects of Masteron, we have broken them down into their separate categories along with all you need to know.
Estrogenic:
Masteron does not aromatize and it does not carry any progestin nature making estrogenic side effects impossible with this steroid. This means gynecomastia and water retention will not be concerns. It also means high blood pressure that is sometimes caused by excess water retention will not be a concern. An anti-estrogen is not needed due to this steroid’s use; as discussed it can have anti-estrogenic effects itself. However, depending on the specific cycle/stack that’s implemented, an anti-estrogen may be needed.
Androgenic:
The side effects of Masteron can include those of an androgenic nature. Androgenic side effects can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Thankfully this hormone carries a moderate level of total androgenic activity despite being a direct derivative of the potent androgen DHT. However, individual sensitivity will play a strong role, this steroid is well-known for greatly enhancing male pattern baldness in sensitive men far more than many anabolic steroids.
An important note; the Drostanolone hormone is not metabolized by the 5-alpha reductase enzyme. This is the enzyme responsible for reducing testosterone to dihydrotestosterone. In the case of Masteron, it’s already DHT; there is no reduction. As there is no reduction, there is no metabolism and nothing to inhibit. This means the androgenic nature of Masteron will not be strongly affected by a 5-alpha reductase inhibitor such as Finasteride.
Due to its androgenic nature, Masteron can produce virilization symptoms in women. Virilization symptoms can include body hair growth, a deepening of the vocal chords and clitoral enlargement. Virilization symptoms have been well-noted in breast cancer treatment plans, but this is normally due to the necessary high doses used to treat such a condition. In a performance capacity, it should be possible to use this steroid without related symptoms with a low dose. However, while individual response will dictate quite a bit, this will not be a primary recommended steroid for female athletes. If it is used and related symptoms begin to show, discontinue use immediately and they will fade away. If the symptoms are ignored, it is very possible they may set in and become irreversible.
Cardiovascular:
Masteron can have a significant effect on cholesterol. This can result in an increase in LDL cholesterol, as well as a decrease in HDL cholesterol with the strongest emphasis on the latter. The total affect on cholesterol will not be as strong as often found in many oral steroids, specifically C17-alpha alkylated steroids. However, the total affect on cholesterol management will be stronger than compared to Nandrolone compounds or the testosterone hormone. It is also possible that Masteron could have a slight negative impact on blood pressure, but this will be a non-issue for most.
Due to the cholesterol effects of Drostanolone, cholesterol management becomes very important with this steroid. Far more important than with basic testosterone cycles or stacks including a basic 19-nor. If you already suffer from high cholesterol you should not use this anabolic steroid. If you are healthy enough for use, maintaining a cholesterol friendly lifestyle is very important. Not only does this mean a healthy diet, but it should be one that includes plenty of omega fatty acids, is limited in saturated fats as well as simple sugars. Plenty of cardiovascular activity is also advised.
Testosterone:
Masteron will significantly suppress natural testosterone production making exogenous testosterone therapy important when using this steroid. Failure to include exogenous testosterone will lead most men to a low testosterone condition, which not only comes with numerous possible symptoms but is also extremely unhealthy.
As most will use Masteron in a cutting cycle, it’s very common not to want to use a lot of testosterone due to the high levels of estrogenic activity it can provide. If this is the case, you will find a low dose of 100-200mg per week of testosterone to be enough to combat suppression and give you the needed testosterone.
Once Masteron is discontinued and all exogenous steroidal hormones have cleared your system, natural testosterone production will begin again. Prior levels will not return to normal over night, this will take several months. Due to the slow recovery, Post Cycle Therapy (PCT) plans are often recommended. This will speed up the recovery greatly; however, it won’t bring your levels back to their peak, this will still take time. A PCT plan will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise and significantly cut down on the total recovery time. This natural recovery does assume no prior low testosterone condition existed. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) through improper supplementation practices.
Hepatotoxicity:
Masteron is not a hepatotoxic anabolic androgenic steroid and will present no stress or damage to the liver.
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